Abstract Familial Adenomatous Polyposis (FAP) is a dominantly inherited bowel cancer predisposition syndrome presenting with hundreds of premalignant polyps in the colon. The standard form of treatment is preventative surgery which involves removal of the entire colon. The rectum and colon may also be removed. Predictive testing is usually done at ten to fourteen years of [...]  Read More →

Abstract Advancements in our understanding of the biology of cancer have progressed dramatically over the past decade. The application of cutting-edge molecular profiling techniques analysing the cancer genome is elucidating an appreciable amount of information. This data is now being integrated into a catalogue that is providing researchers with a revolutionary roadmap of the molecular mechanisms [...]  Read More →

Abstract Primary ovarian cancer is the leading cause of death from gynaecological malignancy and the sixth most common cause of cancer death in Australian women. Our understanding of the underlying pathophysiology of epithelial ovarian cancers is incomplete, which poses difficulties for screening, diagnosis and treatment. This review summarises the current knowledge and debate regarding classification of [...]  Read More →