Apoptosis is considered the main form of cell death in cancer cells undergoing cytotoxic treatments such as chemotherapy and radiotherapy. However, disappointing treatment response rates in some cancers have prompted …
Central sensitisation is the process whereby nociceptive inputs trigger increased excitability and synaptic efficiency of central nociceptive pathways, and is a key process in the development of chronic postoperative pain. …
Glycaemic control around the time of surgery is a critical part of surgical care in diabetic patients. There is a high prevalence of diabetes mellitus worldwide, and the disease is …
The prescription of opioids is increasing worldwide, including in Australia. Consequently, opioid dependence – one of several harms associated with chronic opioid therapy – is now a growing concern. However, …
There are potential benefits and drawbacks when double gloving in the operating theatre. Working in the operating room is associated with a high risk of contact with bodily fluids. To …
Allergic asthma involves type 1 hypersensitivity, which is driven by immunoglobulin E (IgE) dependent immunological mechanisms. Severe asthma is associated with chronically persisting inflammation and is often relatively unresponsive to …
Introduction: The aim of this article is to review the literature and evaluate the evidence of the different medical treatments for stroke prevention in non-valvular atrial fibrillation. Methods: A literature …
Until recently, chronic obstructive pulmonary disease (COPD) received little research attention, as it was perceived as a self- inflicted condition that was difficult to treat. As COPD now affects one …
Introduction: Radiation Therapy (RT) is a common treatment modality for cancer management. Due to specific licensing and expertise requirements, RT tends to be centralised in larger urban centres resulting in …
This review aims to explore the impact that patient attitudes, values and beliefs have on healing and the relevant implications these have for clinical practice and patient centred care. Using …
