A platform for research and endeavour
Welcome to Volume 5, Issue 1 of the Australian Medical Student Journal (AMSJ). The latest issue continues to showcase the vast breadth of medical student and junior doctor research, reviews, …
Appraising laboratory-based cancer research for the medical student
Increasingly clinicians are being asked to participate in translational research–working closely with laboratory scientists to help guide research goals and projects. The work that is done in the laboratory setting …
Recapturing compassion
John was wheeled into hospital on a Friday of a long weekend. He was elderly and frail, with severe Parkinson’s disease. Many hospital staff attended to him – prescribing medications, …
Psychopathy: A disorder or an evolutionary strategy?
I am writing to discuss an interesting construct in psychiatry often referred to as ‘psychopathy’. In psychiatry there is often lively debate about how we should classify and define psychopathology, …
About Helen Caldicott’s guest article
As a university academic whose professional interests include the chemistry of serious reactor accidents I disagree with many of the statements made by Helen Caldicott in her recent article “The …
The α-5 subunit-containing GABA-A receptor: a target for the treatment of cognitive defects
Amnesic effects of benzodiazepines are in part the result of the activity of α5-subunit containing GABAA receptors (GABRA5). Negative modulators at this receptor could improve cognition. In order to explore …
A review of early intervention in youth psychosis
Early intervention in youth psychosis has been a topic of contentious discussion. In particular, there is a lack of consensus regarding how early to treat patients with a psychotic disorder. …
Insights into the application of evolutionary and ecological concepts to cancer treatment via modelling approaches
Therapeutic resistance has been shown to result in poorer clinical outcomes in cancer treatment. It has been proposed that evolutionary adaptations of cancer cells to therapy result in the development …
Glibenclamide therapy as tertiary prevention of melioidosis for Type 2 diabetics.
Background: Melioidosis is a relatively high-incidence, high-mortality tropical infectious disease caused by Burkholderia pseudomallei. To date, the few prevention and management strategies in practice have failed to reduce mortality from …
Resistance to epidermal growth factor receptor inhibitors in non-small cell lung cancer and strategies to overcome it
The War on Cancer has been a particularly long, drawn-out one ever since the National Cancer Act was put into legislation by then U.S. President Richard Nixon. While we attempt …