Paediatric regional anaesthesia: comparing caudal anaesthesia and ilioinguinal block for paediatric inguinal herniotomy

By Robert A Paul | Volume 4, Issue 1 2013

Caudal anaesthesia and ilioinguinal block are effective, safe anaesthetic techniques for paediatric inguinal herniotomy. This review article aims to educate medical students about these techniques by examining their safety and efficacy in paediatric surgery, as well as discussing the relevant anatomy and pharmacology. The roles of general anaesthesia in combination with regional anaesthesia, and that of awake regional... 

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The benefits associated with male HPV vaccination in Australia

By Marcel Boulat & Aishwarya Hatwal | Volume 4, Issue 1 2013

Background: Human papillomavirus (HPV) is a family of highly contagious sexually transmitted viruses which are associated with the development of genital warts and certain HPV related cancers in males and females. After conducting a cost-effective analysis, the Australian Government has decided to expand the school based female only HPV vaccination program to include males commencing in [...]  Read More →

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Treatment of persistent diabetic macular oedema – intravitreal bevacizumab versus laser photocoagulation: A critical appraisal of BOLT Study for an evidence based medicine clinical practice guideline

By Pavani Kurra | Volume 3, Issue 2 2012

Laser photocoagulation has remained the standard of treatment for diabetic macular oedema (DME) for the past three decades. However, it has been shown to be unbeneficial in chronic diffuse DME. Intravitreal bevacizumab (ivB) has been proposed as an alternate and effective treatment of DME. This review evaluates the evidence behind comparing bevacizumab to laser photocoagulation [...]  Read More →

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Seasonal influenza vaccination in antenatal women: Views of health care workers and barriers in the delivery of the vaccine

By Surabhi Khosla | Volume 3, Issue 2 2012

Background: Pregnant women are at an increased risk of developing influenza. The National Health and Medical Research Council recommends seasonal influenza vaccination for all pregnant women who will be in their second or third trimester during the influenza season. The aim of this review is to explore the views of health care workers regarding seasonal [...]  Read More →

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Spontaneous regression of cancer: A therapeutic role for pyrogenic infections?

By Kok-Ho Ho | Volume 3, Issue 2 2012

Spontaneous regression of cancer is a phenomenon that is not well understood. While the mechanisms are unclear, it has been hypothesised that infections, fever and cancer are linked. Studies have shown that infections and fever may be involved in tumour regression and are associated with improved clinical outcomes. This article will examine the history, evidence [...]  Read More →

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The therapeutic potentials of cannabis in the treatment of neuropathic pain and issues surrounding its dependence

By Stephanie Sargent | Volume 3, Issue 2 2012

Cannabis is a promising therapeutic agent, which may be particularly beneficial in providing adequate analgesia to patients with neuropathic pain intractable to typical pharmacotherapy. Cannabinoids are the lipid-soluble compounds that mediate the analgesic effects associated with cannabis by interacting with the endogenous cannabinoid receptors CB1 and CB2, which are distributed along neurons associated with pain [...]  Read More →

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A biological explanation for depression: The role of interleukin-6 in the aetiology and pathogenesis of depression and its clinical implications

By Stephy Zhang | Volume 3, Issue 2 2012

Depression is one of the most common health problems addressed by general practitioners in Australia. It is well known that biological, psychosocial and environmental factors play a role in the aetiology of depression. Research into the possible biological mechanisms of depression has identified interleukin-6 (IL-6) as a potential biological correlate of depressive behaviour, with proposed [...]  Read More →

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Where to from here for Australian childhood obesity?

By Jasmine Antoine | Volume 3, Issue 2 2012

Aim: At least one in twenty Australian school children are obese. [1] The causes and consequences of childhood obesity are well documented. This article examines the current literature on obesity management in school-aged, Australian children. Methods: A systematic review was undertaken to examine the efficacy of weight management strategies of obese Australian school-aged children. Search [...]  Read More →

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The future of personalised cancer therapy, today

By May Wong | Volume 3, Issue 1 2012

With the human genome sequenced a decade ago and the concurrent development of genomics, pharmacogenetics and proteomics, the field of personalised cancer treatment appears to be a maturing reality. It is recognised that the days of ‘one-sizefi ts-all’ and ‘trial and error’ cancer treatment are numbered, and such conventional approaches will be refined. The rationale [...]  Read More →

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Is Chlamydia trachomatis a cofactor for cervical cancer?

By Surabhi Khosla | Volume 3, Issue 1 2012

Introduction The most recent epidemiological publication on the worldwide burden of cervical cancer has reported that cervical cancer (0.53 million cases) was the third most common female cancer reported in 2008 after breast (1.38 million cases) and colorectal cancer (0.57 million cases). [1] Cervical cancer is the leading source of cancer-related death among women in [...]  Read More →

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ISSN (Print): 1837-171X
ISSN (Online): 1837-1728
ABN: 51967802511