The impaired student: Substance abuse in medical students

By Lewis Fry | Volume 6, Issue 2 2015

Substance use disorder has been a significant issue within the medical profession throughout history. It is recognised as an important issue of concern, particularly due to its associated mortality, morbidity and social consequences. Although a substantial body of literature addresses this issue amongst doctors, there is little discussion focusing on medical students. This review summarises […]  Read More →

Download PDF | Read the full article online

Is cellular senescence a viable strategy and endpoint for oncological control?

By Kok-Ho Ho | Volume 6, Issue 2 2015

Apoptosis is considered the main form of cell death in cancer cells undergoing cytotoxic treatments such as chemotherapy and radiotherapy. However, disappointing treatment response rates in some cancers have prompted a rethink regarding oncological control methods. Cellular senescence has emerged as a possible tumour suppression strategy that may effectively control cancer cells when apoptosis fails. […]  Read More →

Download PDF | Read the full article online

Perioperative pain management – should we pre-empt or prevent pain?

By Dr. Lukman Anderson | Volume 6, Issue 2 2015

Central sensitisation is the process whereby nociceptive inputs trigger increased excitability and synaptic efficiency of central nociceptive pathways, and is a key process in the development of chronic postoperative pain. Pre-emptive analgesia, whereby analgesia is given prior to surgical incision, has previously been advocated as a method of decreasing the process of central sensitisation and […]  Read More →

Download PDF | Read the full article online

Perioperative glycaemic control in diabetic surgical patients – review

By Andrew Zhang | Volume 6, Issue 2 2015

Glycaemic control around the time of surgery is a critical part of surgical care in diabetic patients. There is a high prevalence of diabetes mellitus worldwide, and the disease is becoming more common in both medical and surgical patients. Even in patients without diabetes, surgery disrupts usual diabetic management and glucose homeostasis, often resulting in […]  Read More →

Download PDF | Read the full article online

Risk factors for iatrogenic opioid dependence: An Australian perspective

By Hannah Hartman | Volume 6, Issue 2 2015

The prescription of opioids is increasing worldwide, including in Australia. Consequently, opioid dependence – one of several harms associated with chronic opioid therapy – is now a growing concern. However, the risk factors for iatrogenic opioid dependence are not well understood in an Australian context. The available Australian evidence for these risks are reviewed and […]  Read More →

Download PDF | Read the full article online

Double gloving in the operating theatre: The benefits and the potential drawbacks

By Matthew Papageorgiou | Volume 6, Issue 2 2015

There are potential benefits and drawbacks when double gloving in the operating theatre. Working in the operating room is associated with a high risk of contact with bodily fluids. To prevent breaches of surgical gloves in theatre it has been suggested in the literature that using two pairs of gloves (double gloving) could provide benefit.  […]  Read More →

Download PDF | Read the full article online

Pathogenesis of severe allergic asthma and the therapeutic use of anti- immunoglobulin E antibody

By Rukaiya Malik | Volume 6, Issue 1 2015

Allergic asthma involves type 1 hypersensitivity, which is driven by immunoglobulin E (IgE) dependent immunological mechanisms. Severe asthma is associated with chronically persisting inflammation and is often relatively unresponsive to conventional treatment with corticosteroids. This review article summarises the best treatment for severe persistent asthmatics based on current understanding of its pathogenesis. The... 

Download PDF | Read the full article online

Stroke prevention in non-valvular atrial fibrillation: advances in medical therapy

By Dr. Karishma Zobair | Volume 6, Issue 1 2015

Introduction: The aim of this article is to review the literature and evaluate the evidence of the different medical treatments for stroke prevention in non-valvular atrial fibrillation. Methods: A literature search using MEDLINE plus OvidSP, PubMed, CINAHL and the New England Journal of Medicine databases was performed with the search terms stroke prevention, atrial fibrillation, […]  Read More →

Download PDF | Read the full article online

Chronic obstructive pulmonary disease: extrapulmonary manifestations, pulmonary rehabilitation programs and the role of nutritional biomarkers on patient outcomes

By Melissa McDonald | Volume 6, Issue 1 2015

Until recently, chronic obstructive pulmonary disease (COPD) received little research attention, as it was perceived as a self- inflicted condition that was difficult to treat. As COPD now affects one in seven Australians over 40 and is a leading cause of disease burden and death, research into this condition has intensified. Traditionally, research focused on […]  Read More →

Download PDF | Read the full article online

Does increased geographical distance to a radiation therapy facility act as a barrier to seeking treatment?

By Divya Kiran Sharma | Volume 6, Issue 1 2015

Introduction: Radiation Therapy (RT) is a common treatment modality for cancer management. Due to specific licensing and expertise  requirements,  RT  tends  to  be  centralised  in  larger urban  centres  resulting  in  restricted  geographical  access  for many. Several studies conducted have examined the relationship between distance to treatment and utilisation of RT, however there remains a gap […]  Read More →

Download PDF | Read the full article online